产品货号:
Z22291
中文名称:
NUP160抗体
英文名称:
Anti-NUP160 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-NUP160 Antibody |
| 指标别名 | KIAA0197,NUP120,Nuclear pore complex protein Nup160,160kDa nucleoporin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NUP160 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NUP160 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human NUP160.The immunogen is located within the last 50 amino acids of NUP160. |
| 计算分子量 | 162kDa |
| 成分 | NUP160 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NUP160 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm.The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107,NUP133,NUP96,and mammalian homolog of yeast sec13p.While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore,a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1,Mad2,Bub3 and Cdc20.Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions.NUP160 has recently been identified as an HIV dependency factor (HDF),suggesting that NUP160 may be an important drug target in HIV treatment.Multiple isoforms of NUP160 are known to exist. |
| Uniprot ID | Q12769 |
| 基因名全称 | Nucleoporin 160kDa |
| 蛋白名全称 | Nucleoporin 160kDa |
| 推荐稀释比 | NUP160 antibody can be used for detection of NUP160 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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